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Concept of human bowel flora as a
living organ


It is useful to compare the human faecal flora to a living organ because its major component is a complex mass of living cells. Furthermore, it interacts with the human body and the human body interacts with it. Given that the human body is made up of approximately 1014 cells - while 1 x 1013 are body cells, about 9 x 1013 cells are bacteria contained within the bowel. Hence, purely on cell count we are 10% human and 90% stool! 1

The body is large in size because it contains much connective tissue, whereas the human flora exists as a small, tightly packed mass of bacterial cells. If we conceptualise human bowel flora as an organ it helps us understand how it can function as a normal, healthy organ or as an organ that can undergo various illness states. Such a concept is not far removed from the standard medical concepts of healthy or diseased organs such as liver (hepatitis, alcohol-induced disease etc), lung (pneumonia, asthma, emphysema etc), heart (coronary artery disease, rheumatic fever etc). Generally, each organ develops disorders peculiar to the structure and function of that organ.