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  PTRC was established by Dr Thomas Borody, gastroenterologist and director of the Centre for Digestive Diseases (CDD), Five Dock and director of PTRC, Five Dock. Dr Borody originally conceived the idea for creating such a centre in the year 2000. He wanted to provide new alternative treatments for patients who suffer from gastrointestinal problems using human probiotic infusions (HPIs).

PTRC has 3 registered nurses, a technical officer and a receptionist. Dr Borody consults off site at CDD prior to treatment at PTRC.

PTRC has 11 fully equipped procedure rooms, 1 processing room/laboratory and 2 consult rooms. PTRC is the only centre in the world that performs Human Probiotic Infusions (HPIs).